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A 12-week trial at 1.0mg showed semaglutide reduced energy intake by approximately 35% versus placebo

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Gut Microbes (2021) 13:119

These medications are generally considered for adults with: BMI 30 kg/m or BMI 27 kg/m with conditions such as: Type 2 diabetes High blood pressure Fatty liver Obstructive sleep apnea High cholesterol PCOS Knee osteoarthritis For Asian Indians , treatment decisions may be individualized because obesity-related complications often occur at lower BMI values

StatPearls Ilina A, Khavinson V, Linkova N, Petukhov M (2022) Neuroepigenetic mechanisms of action of ultrashort peptides in Alzheimers disease