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Discovered in 2015, it has become a central tool in research on AMPK signalling, metabolic homeostasis, and mitochondrial-nuclear crosstalk

Recent studies have found that the gene expression of ferroptosis in neurons peaks at the injury center within 28 days after spinal cord injury, with neurons being more prone to ferroptosis than other neural cells at the time of injury [17]

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Compounds at 500 mM in DMSO stocks were dispensed into selected crystal drops as singletons using an Echo 550 liquid handler to give a final concentration of 50 mM (10% DMSO final concentration)